英文名称 Anti-IDE
中文名称 胰岛素降解酶抗体
胰岛素降解酶抗体别 名 BC2; Insulin degrading enzyme; FLJ35968; insulin protease; insulinase; insulysin; Abeta-degrading protease; FLJ35968; Ide; IDE_HUMAN; Insulin-degrading enzyme; OTTHUMP00000020097.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Mouse
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、胰岛素降解酶抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 肿瘤 心血管 细胞生物 免疫学 神经生物学 信号转导 生长因子和激素 糖尿病 内分泌病 Alzheimer's
蛋白分子量 predicted molecular weight: 117kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human IDE N-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰岛素降解酶抗体产品介绍 Insulysin was identified nearly a century ago as an enzyme responsible for the degradation of insulin in cells, although the precise interactions between insulin and insulysin remain elusive. Human insulysin was cloned in 1988, and shown to be a 118 kDa protein that exists primarily as a homodimer, and perhaps also complexed with other molecules. The sequence is well conserved between humans, rats and mice, and the antibody recognizes these species. Insulysin is a metalloproteinase of the clan ME, family M16, which contains an active site HxxEH, a reversal of the canonical HExxH zinc binding motif. Considered a zinc metalloproteinase, the activity of insulysin can be blocked with EDTA or 1-10 phenanthroline. In addition to the active metalloproteinase domain, insulysin contains a second metalloproteinase site which is considered catalytically inactive, and is thought to assist in substrate binding. Insulysin is most closely related to the bacterial proteinase pitrilysin, (the human orthologue of which appears to be MPRP1) and the mammalian proteinsae nardilysin. Generally thought to be a cytoplasmic protein, insulysin has been isolated from many different tissues and cell lines, and can degrade intact insulin, insulin B chain, glucagon, denatured hemoglobin, alpha amyloid protein, TGF alpha and amylin. Recent work implicates insulysin in clearing beta amyloid plaques from the brain, and has generated much interest in Alzheimer’s disease research. The pH optimum for insulysin is basic, pH 8.5, which also distinguishes it from other
Alpha-Synuclein/Syn/SNCA 核突触蛋白α抗体 规格 0.1ml
ALPK3 α蛋白激酶3抗体(心肌) 规格 0.2ml
ALR 肝再生增强因子抗体 规格 0.1ml
ALS2CR4 肌萎缩侧索硬化症相关蛋白4抗体 规格 0.2ml
ALS2CR8 肌萎缩侧索硬化2染色体区域候选蛋白8抗体 规格 0.2ml
ALT1 谷丙氨酸氨基转移酶1抗体 规格 0.1ml
AMACR/P504S α-甲基酰基辅酶A消旋酶抗体 规格 0.1ml
AMBP/Alpha 1 microglobulin α1微球蛋白抗体 规格 0.2ml
AMBRA1 自噬相关基因AMBRA1抗体 规格 0.2ml
AMFR/Gp78/RNF45 环指蛋白45/自分泌运动因子受体抗体 规格 0.2ml
AMH/MIS Muellerian缪勒管激素抑制因子抗体 规格 0.2ml
AMID/AIFM2 线粒体凋亡诱导因子2抗体 规格 0.2ml
AMIGO1 粘附分子IgG样结构域蛋白1抗体 规格 0.2ml
AM胰岛素降解酶抗体IGO3 粘附分子IgG样结构域蛋白3抗体 规格 0.2ml
Amisyn 突触融合结合蛋白6抗体 规格 0.2ml
AMN1 细胞核重定位及纺锤体检查点蛋白AMN1抗体 规格 0.2ml
AMP deaminase 1 腺苷单磷酸脱氨酶1抗体 规格 0.2ml
AMPD3 红细胞腺苷脱氨酶3抗体 规格 0.2ml
Amphetamine(2A3F6) 苯丙胺单克隆抗体(安非他明) 规格 0.1ml
Amphiphysin 神经元突触前膜蛋白抗体 规格 0.2ml
Amphiregulin 双调蛋白(结肠直肠细胞源性生长因子)抗体 规格 0.1ml
AMPK alpha 1/PRKAA1 腺苷单磷酸活化蛋白激酶α1抗体 规格 0.1ml
AMPK beta 1 腺苷单磷酸活化蛋白激酶β1抗体 规格 0.1ml
AMPK beta 2 腺苷单磷酸活化蛋白激酶β2抗体 规格 0.2ml
AMPK gamma 1 腺苷酸活化蛋白激酶γ1抗体 规格 0.2ml
更多胰岛素降解酶抗体价格、 胰岛素降解酶抗体批发价、胰岛素降解酶抗体品牌、厂家及抗体详细说明书,都可跟我们销售人员索取。