英文名称 Anti-Phospho-Insulin Receptor Beta(Tyr1185)
中文名称 磷酸化胰岛素受体β抗体
磷酸化胰岛素受体β抗体别 名 Insulin Receptor (phospho Y1185); Insulin Receptor (phospho Try1185); CD 220; CD220; CD220 antigen; HHF 5; HHF5; HIR B; INSR; INSR; Insulin receptor; Insulin receptor subunit beta; IR; INSR_HUMAN.
浓 度 1mg/1ml
规 格 0.1ml/100μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit
产品类型 一抗 磷酸化抗体
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、磷酸化胰岛素受体β抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 免疫学 信号转导 干细胞 细胞粘附分子
蛋白分子量 predicted molecular weight: 87kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human ITGB3 around the phosphorylation site of Tyr773
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The ITGB3 (Integrin beta chain beta 3) protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface 磷酸化胰岛素受体β抗体mediated signalling.
Function : Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Subunit : Heterodimer of an alpha and a beta subunit. Beta-3 associates with either alpha-IIb or alpha-V. Isoform Beta-3C interacts with FLNB. Interacts with COMP.Interacts with SYK; upon activation by ITGB3 promotes platelet adhesion. Interacts with MYO10.
Rabbit Anti-Guinea pig IgG/Cy3 Cy3标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/Cy5 Cy5标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/Cy5.5 Cy5.5标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/Cy7 Cy7标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/FITC FITC标记的兔抗豚鼠IgG 规格 0.3ml
Rabbit Anti-Guinea pig IgG/Gold 胶体金标记的兔抗豚鼠IgG 规格 0.5ml
Rabbit Anti-Guinea pig IgG/HRP 辣根过氧化物酶标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/PE PE标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/PE-Cy3 PE-Cy3标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/PE-CY5 PE-CY5标记的兔抗豚鼠IgG 规格 0.1ml
R磷酸化胰岛素受体β抗体abbit Anti-Guinea pig IgG/PE-Cy5.5 PE-Cy5.5标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/PE-Cy7 PE-Cy7标记的兔抗豚鼠IgG 规格 0.1ml
Rabbit Anti-Guinea pig IgG/RBITC 罗丹明标记的兔抗豚鼠IgG 规格 0.3ml
更多磷酸化胰岛素受体β抗体价格、 磷酸化胰岛素受体β抗体批发价、 磷酸化胰岛素受体β抗体品牌、厂家及抗体详细说明书,都可跟我们销售人员索取。