英文名称 Anti-Gemin 2
中文名称 运动神经元存活蛋白结合蛋白1抗体
运动神经元存活蛋白结合蛋白1抗体别 名 Component of gems 2; GEMI2_HUMAN; Gemin-2; gemin2; SIP 1; SIP-1; SIP1; SIP1 delta; SMN interacting protein 1; SMN interacting protein 1 delta; SMN-interacting protein 1; Survival interacting protein 1; Survival of motor neuron protein interacting protein 1; Survival of motor neuron protein-interacting protein 1. survival of motor neuron protein interacting protein 1; SMN protein interacting protein 1; KIAA0569; SIP 1; SIP1; SMADIP 1; SMADIP1.
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、运动神经元存活蛋白结合蛋白1抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 免疫学 神经生物学
蛋白分子量 predicted molecular weight: 30kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human SIP1 C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Smad Interacting Protein 1 (SIP1) is observed in neural crest derived cells (peripheric nervous system, enteric nervous system, facial neurectoderm and cranial nerve ganglia), central nervous system, genital tubercle, muscles and kidneys in the developing human. SIP1 belongs to the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins and contains a SMAD-binding domain, a homeodomain and two clusters of zinc fingers on the N- and C-termini. SIP1 can be induced by TGF. SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR). Patients with SIP1 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart disease. SIP1 is also involved in the regulation of epithelial to mesenchymal transition, an important process in tumor progression.
Function : The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
Subunit : Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with GEMIN5.
Subcellular Location : Nucleus, gem. Cytoplasm. Note=Localized in subnuclear structures next to coiled bodies, called gems, which are highly enriched in spliceosomal snRNPs. Also found in the cytoplasm.
Similarity : Belongs to the gemin-2 family.
Database links :
Entrez Gene: 8487 Human
Entrez Gene: 66603 Mouse
Omim: 602595 Human
SwissProt: O14893 Human
SwissProt: Q9CQQ4 Mouse
SwissProt: O42260 Xenopus laevis
Unigene: 652307 Human
Unigene: 35353 Mouse
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ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
运动神经元存活蛋白结合蛋白1抗体ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
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企业名称
上海研生生化试剂有限公司
企业信息已认证
企业类型
信用代码
310112001038197
成立日期
2011-01-12
注册资本
100
经营范围
上海研生实业有限公司
公司地址
上海市漕宝路66号20F
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