酪氨酸蛋白激酶受体B2抗体

英文名称  Anti-EphB2 R 

中文名称  酪氨酸蛋白激酶受体B2抗体 

酪氨酸蛋白激酶受体B2抗体别    名  Eph receptor B2; Developmentally regulated EPH related tyrosine kinase; DRT; ELK related protein tyrosine kinase; EPH tyrosine kinase 3; EphB2; Ephrin type B receptor 2; EPHT 3; ERK; ETECK; Nuk; Prkm 5; Receptor protein tyrosine kinase HEK 5, Sek 3; Tyro 5; Tyrosine protein kinase receptor CEK 5; Tyrosine protein kinase receptor EPH 3; Tyrosine protein kinase receptor QEK 5. 

浓    度  1mg/1ml 

规 格  0.1ml/100μg  0.2ml/200μg     

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Dog

产品类型  一抗    

公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体，产品货期短、酪氨酸蛋白激酶受体B2抗体品质保证、全国免邮，并提供抗体相应实验技术指导。

研究领域  肿瘤 免疫学 生长因子和激素  

蛋白分子量  predicted molecular weight: 114kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human EphB2 R C-terminus 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Eph receptors play important roles in axon guidance at the midline. In the auditory system, growth of axons across the midline is an important determinant of auditory function. The avian cochlear nucleus, n. magnocellularis (NM), makes bilateral projections to its target, n. laminaris (NL). 

Subunit : Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses. Interacts (via PDZ-binding motif) with GRIP1 and PICK1 (via PDZ domain). Interacts with ARHGEF15; mediates ARHGEF15 phosphorylation, ubiquitination and degradation by the proteasome. Interacts with AQP1; involved in endolymph production in the inner ear.

Subcellular Location : Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite.

Tissue Specificity : Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.

DISEASE : Defects in EPHB2 may be a cause of susceptibility to prostate cancer (PC) [MIM:176807]. It is a malignancy originating in tissues of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. Note=EPHB2 mutations have been found in a prostate 酪氨酸蛋白激酶受体B2抗体cancer cell line derived from a brain metastasis.

Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.

Contains 1 Eph LBD (Eph ligand-binding) domain. 

Contains 2 fibronectin type-III domains. 

Contains 1 protein kinase domain. 

Contains 1 SAM (sterile alpha motif) domain.

生长因子和激素（ Growth Factor and Hormones）

EphB2受体(Ephrin type-B receptor 2)在细胞生长、分化和信号转导过程中具有重要作用。有报道：EphB2受体(ephrinB2受体) 在中枢神经组织，肿瘤组织有较强的表达。促进肿瘤细胞浸润和新生血管形成.

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

酪氨酸蛋白激酶受体B2抗体ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2

更多酪氨酸蛋白激酶受体B2抗体价格、 酪氨酸蛋白激酶受体B2抗体批发价、 酪氨酸蛋白激酶受体B2抗体品牌、厂家及抗体详细说明书，都可跟我们销售人员索取。