内皮素-1抗体

英文名称  Anti-ET-1 

中文名称  内皮素-1抗体 

内皮素-1抗体 别    名  EDN1_HUMAN; Big endothelin 1; EDN 1; EDN1; EDN1 protein; Endothelin1; Endothelin 1; Endothelin-1; ET 1; ET1; OTTHUMP00000039245; PPET1; Preproendothelin 1; Preproendothelin1. 

浓    度  1mg/1ml 

规 格  0.1ml/100μg  0.2ml/200μg  1ml/1mg   

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat

产品类型  一抗    

公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体，产品货期短、内皮素-1抗体品质保证、全国免邮，并提供抗体相应实验技术指导。

研究领域  心血管 神经生物学  

蛋白分子量  predicted molecular weight: 22kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human ET-1 N-terminus 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

内皮素-1抗体Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Function : Endothelins are endothelium-derived vasoconstrictor peptides.

Subcellular Location : Secreted.

Tissue Specificity : Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Similarity : Belongs to the endothelin/sarafotoxin family.

Database links : UniProtKB/Swiss-Prot: P05305.1

内皮素(Endothelin，ET)是一种强的血管收缩剂，分为ET-1,ET-2,ET-3 三种，ET-1主要在内皮细胞中表达,而ET-2和ET-3则主要在神经系统中表达。ET具有广泛的生物学作用。此抗体是ET-1特异性抗体，与ET-2,ET-3无交叉反应。

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