微管相关末端结合蛋白2抗体

英文名称  Anti-EB2 

中文名称  微管相关末端结合蛋白2抗体 

微管相关末端结合蛋白2抗体别    名  APC binding protein EB2; APC-binding protein EB2; EB1; EB2; End binding protein 2; End-binding protein 2; H.sapiens mRNA for novel T cell activation protein; MAPRE2; MARE2_HUMAN; Microtubule associated protein RP/EB family member 2; Microtubule-associated protein RP/EB family member 2; T cell activation protein EB1 family. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg     

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Cow, Horse

产品类型  一抗   

公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体，产品货期短、微管相关末端结合蛋白2抗体品质保证、全国免邮，并提供抗体相应实验技术指导。

研究领域  细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质  

蛋白分子量  predicted molecular weight: 36kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human End binding protein 2 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

微管相关末端结合蛋白2抗体（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012].

Function : May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.

Subunit : Interacts with DCTN1. Binds to the C-terminal domain of APC. Binds monomeric and polymerized tubulin.

Subcellular Location : Cytoplasm, cytoskeleton.

Tissue Specificity : Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.

Similarity : Belongs to the MAPRE family.

Contains 1 CH (calponin-homology) domain.

Contains 1 EB1 C-terminal domain.

Database links : UniProtKB/Swiss-Prot: Q15555

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