ETS1相关蛋白2抗体
别 名 EAP 2; EAP II; EAP2; EAPII; ETS 1 associated protein 2; ETS 1 associated protein II; ETS1 associated protein 2; ETS1-associated protein 2; ETS1-associated protein II; tdp2; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; TTRAP; TYDP2_HUMAN; Tyr DNA phosphodiesterase 2; Tyr-DNA phosphodiesterase 2; Tyrosyl DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; 5''-Tyr-DNA phosphodiesterase; 5''-tyrosyl-DNA phosphodiesterase; AD 022; AD022; MGC111021; MGC9099.
浓 度 1mg/1ml
英文名称 Anti-ETS1 associated protein II/EAPII
中文名称 ETS1相关蛋白2抗体
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、ETS1相关蛋白2抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 肿瘤 免疫学 信号转导 转录调节因子
蛋白分子量 predicted molecular weight: 41kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human ETS1 associated protein II/EAPII
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable ETS1相关蛋白2抗体 the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Function : DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Subunit : Interacts with TRAF2, TRAF3, TRAF5, TRAF6, TNFRSF8/CD30, TNFRSF5/CD40, TNFRSF1B/TNF-R75, ETS1, ETS2, FLI1, SMAD3 and ACVR1B/ALK4.
Subcellular Location : Nucleus. Nucleus, PML body.
Tissue Specificity : Widely expressed.
Database links : Belongs to the CCR4/nocturin family.
TGF-β1 转移生长因子-β1
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Mouse Histamine Elisa kit 小鼠组胺(Histamine)
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Mouse TGFα ELISA Kit 小鼠转化生长因子α(TGFα)ELISA Kit
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Mouse Tumor necrosis factor soluble receptorⅡ ELISA KIT 小鼠肿瘤坏死因子可溶性受体Ⅱ(TNFsRⅡ)
Mouse Tumor necrosis factor β ELISA KIT 小鼠肿瘤坏死因子β(TNFβ)
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Mouse GCP-2 ELISA Kit 小鼠中性粒细胞趋化蛋白-2(GCP-2)
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Mouse LBP ELISA Kit 小鼠脂多糖结合蛋白(LBP)
Mouse LPS ELISA Kit 小鼠脂多糖(LPS)
Mouse Lamina Propria Lymphocyte ELISA Kit 小鼠脂蛋白脂酶(LPL)
Mouse lipoprotein-associated phospholipase A2 ELISA Kit 小鼠脂蛋白磷脂酶A2(Lp-PLA2)
Mouse Lpa ELSIA Kit 小鼠脂蛋白(Lpa)
Mouse PCNA ELISA Kit 小鼠增殖细胞抗原(PCNA)
Mouse apoB100 ELISA Kit 小鼠载脂蛋白B100(apoB100)
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ETS1相关蛋白2抗体Mouse PROG ELISA Kit 小鼠孕酮(PROG)
Mouse Progesterone ELISA kit 小鼠孕激素(Progesterone)
Mouse inducible nitric oxide synthase ELISA KIT 小鼠诱导型一氧化氮合成酶(iNOS)
Mouse Free-T3 ELISA Kit 小鼠游离三碘甲状腺原氨酸(Free-T3)
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企业名称
上海研生生化试剂有限公司
企业信息已认证
企业类型
信用代码
310112001038197
成立日期
2011-01-12
注册资本
100
经营范围
上海研生实业有限公司
公司地址
上海市漕宝路66号20F
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