钩藤碱

钩藤碱
Rhynchophylline
CAS编号：76-66-4
别　　名：钩藤碱;鉤藤鹼;RHYNCHOLPHYLLINE;RHYNCHOPHYLLINE;MITRINERMINE;16e,20-alpha)-(7-bet;mitrinermin;rhynchophyllin;UNCARINE D(P);rhyncophylline;Mitrinermin; Mitrinermine; Rhyncophylline; Rhynchophyllin;Rhynocophylline;Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7-beta,16E,20-alpha)- ;
分子式：C22H28N2O4
钩藤碱--(Rhynchophylline)的详细信息
【提取来源】钩藤.
钩藤碱【性状】结晶体(甲醇)。熔点216℃。旋光度-14.7°(c=2.5，氯仿)。溶于氯仿，尚可溶于丙酮、乙醇、苯，微溶于和乙酸乙酯。天然存在于茜草科植物钩藤[Uncaria rhynchophylla (Miq. ) Jacks.]等植物中。可用化学合成法制得。
【药理作用】本品有抑制呼吸中枢和离体肠管及兴奋大鼠离体子宫，降低血压，抗血小板聚集并有促进已聚集血小板解聚的作用。还能改善红细胞的变形能力，抑制不良因素对红细胞变形能力的损害。临床用于治疗高血压病，对I、II期高血压有一定的疗效。
【用法】流动相: 甲醇-水(55∶45) , 含0.01 mol/L三乙胺, 冰醋酸调pH 7.5 。流速: 1.0 mL/min, 检测波长254nm。（仅供参考）
钩藤碱 Rhynchophylline 对照品 HPLC≥98% 20mg
钩藤碱温馨提示：仅供科研实验，不得用于其它用途！
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