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胞浆动力蛋白中间链1抗体

供货周期：一周

品牌： Abcam

规格： 0.2ml/200μg

货号：

CAS号：

报价： ¥1

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产品介绍

胞浆动力蛋白中间链1抗体英文名称 Anti-DYNC1I1

中文名称胞浆动力蛋白中间链1抗体

别名 dynein, cytoplasmic, intermediate polypeptide 1; cytoplasmic dynein 1 intermediate chain 1; DH IC-1; dynein intermediate chain 1, cytosolic; cytoplasmic dynein intermediate chain 1; DC1I1_HUMAN; DYNC1I1; DNCI1; DNCIC1; Dynein cytoplasmic intermediate polypeptide 1.

公司胞浆动力蛋白中间链1抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。

浓度 1mg/1ml

规格 0.1ml/100μg 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat

产品类型一抗

研究领域细胞生物神经生物学信号转导细胞粘附分子细胞骨架

蛋白分子量 predicted molecular weight: 71kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human DYNC1I1

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胞浆动力蛋白中间链1抗体产品介绍 The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. [provided by RefSeq, Jul 2008].

Function : Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

Subunit : Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNC1H1. Interacts with DYNLT1 and DYNLT3. Interacts with DCNT1.

Subcellular Location : Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.

Similarity : Belongs to the dynein intermediate chain family.

Contains 7 WD repeats.

Database links : UniProtKB/Swiss-Prot: O14576

【存储要求】连续使用时4°C存储，保质期六个月；胞浆动力蛋白中间链1抗体期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。

实验的用途：

1）WB：Western Blotting 免疫印迹

2）IH：Immunohistochemistry 免疫组化

3）IH(P)：Immunohistochemistry Parraffin sections 免疫组化(石蜡)

4）IH(F)：Immunohistochemistry Frozen sections 免疫组化(冰冻)

5）IC：Immunocytochemistry 免疫细胞化学

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上海基免实业有限公司

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310116002801941

成立日期

2013-03-11

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胞浆动力蛋白中间链1抗体由上海基免实业有限公司为您提供，货号，规格：0.2ml/200μg ，CAS号：，如您想了解更多关于胞浆动力蛋白中间链1抗体价格、胞浆动力蛋白中间链1抗体结构式、批发、用途等信息，欢迎咨询。除供应胞浆动力蛋白中间链1抗体外，还可为您提供虾淀粉酶α(Amyα)检测试剂盒、鸭免疫球蛋白M(IgM)检测试剂盒、玉米赤霉烯酮(ZEN)检测试剂盒等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海基免客户服务电话，售前、售后均可联系。

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