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多巴胺β羟化酶抗体

供货周期： 7天

品牌： Abcam

型号： 0.2ml/200μg

货号：

报价： ¥1

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产品介绍

多巴胺β羟化酶抗体英文名称 Anti-DBH

中文名称多巴胺β羟化酶抗体

别名 DBH; DBM; Dopamine beta hydroxylase; Dopamine- Beta-Hydroxylase; Dopamine beta monooxygenase; DOPO_RAT.

公司多巴胺β羟化酶抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。

浓度 1mg/1ml

规格 0.1ml/100μg 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat

产品类型一抗

研究领域肿瘤神经生物学合成与降解

蛋白分子量 predicted molecular weight: 70kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human DBH C-terminus

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

多巴胺β羟化酶抗体产品介绍 Dopamine-beta-Hydroxylase (DBH), Dopamine can be transformed into Noradrenalin. Conversion of dopamine to noradrenaline. [SUBUNIT] Homotetramer composed of two non-covalently bound disulfide-linked dimers. [SUBCELLULAR LOCATION] Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (Potential). Belongs to the copper type II ascorbate-dependent monooxygenase family.

Function : Conversion of dopamine to noradrenaline.

Subunit : Homotetramer composed of two non-covalently bound disulfide-linked dimers (By similarity).

Subcellular Location : Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen (By similarity).

Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (By similarity).

Tissue Specificity : Chromaffin granules of the adrenal medulla and synaptic vesicles of the sympathetic nervous system.

Similarity : Belongs to the copper type II ascorbate-dependent monooxygenase family.

Contains 1 DOMON domain.

Database links : UniProtKB/Swiss-Prot: Q05754.1

Dopamine-β-Hydroxylase（DBH）—多巴胺β羟化酶。可以将多巴胺转化成去甲肾上腺素。是肾上腺素能神经元的标志。

【存储要求】连续使用时4°C存储，保质期六个月；多巴胺β羟化酶抗体期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。

实验的用途：

1）WB：Western Blotting 免疫印迹

2）IH：Immunohistochemistry 免疫组化

3）IH(P)：Immunohistochemistry Parraffin sections 免疫组化(石蜡)

4）IH(F)：Immunohistochemistry Frozen sections 免疫组化(冰冻)

5）IC：Immunocytochemistry 免疫细胞化学