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当前位置: 上海基免 > 生物分子 > S期激酶活化蛋白DBF4A抗体

S期激酶活化蛋白DBF4A抗体

供货周期: 一周
品牌: Abcam
规格: 0.2ml/200μg
货号:
CAS号:
报价: ¥1
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产品介绍
S期激酶活化蛋白DBF4A抗体英文名称  Anti-DBF4A 
中文名称  S期激酶活化蛋白DBF4A抗体 
别    名  Activator of S phase kinase; ASK; Chiffon homolog A; DBF4; DBF4 type zinc finger containing protein 1; DBF4-type zinc finger-containing protein 1; DBF4A; DBF4A_HUMAN; Protein DBF4 homolog A; ZDBF1. 
公司S期激酶活化蛋白DBF4A抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。
浓    度  1mg/1ml 
规 格  0.2ml/200μg          
抗体来源  Rabbit  
克隆类型  polyclonal 
交叉反应  Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep   
产品类型  一抗    
研究领域  细胞生物 信号转导 细胞周期蛋白 表观遗传学  
蛋白分子量  predicted molecular weight: 77kDa 
性    状  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human DBF4A 
亚    型  IgG 
纯化方法  affinity purified by Protein A 
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 
(石蜡切片需做抗原修复) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
S期激酶活化蛋白DBF4A抗体产品介绍 Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Function : Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. 
Subunit : Forms a complex with CDC7. Note that CDC7 forms distinct complex either with DBF4A or DBF4B. Such complexes are stable upon replication stress. Interacts with MEN1, MCM2, ORC2, ORC4 and ORC6. 
Subcellular Location : Nucleus. 
Tissue Specificity : Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR. 
Similarity : Contains 2 BRCT domains. 
Contains 1 DBF4-type zinc finger. 
Database links : UniProtKB/Swiss-Prot: Q9UBU7.1
【存储要求】连续使用时4°C存储,保质期六个月;S期激酶活化蛋白DBF4A抗体期存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。
实验的用途:
1)WB:Western Blotting 免疫印迹
2)IH:Immunohistochemistry 免疫组化
3)IH(P):Immunohistochemistry Parraffin sections 免疫组化(石蜡)
4)IH(F):Immunohistochemistry Frozen sections 免疫组化(冰冻)
5)IC:Immunocytochemistry 免疫细胞化学
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310116002801941

成立日期

2013-03-11

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S期激酶活化蛋白DBF4A抗体由上海基免实业有限公司为您提供,货号,规格:0.2ml/200μg ,CAS号:,如您想了解更多关于S期激酶活化蛋白DBF4A抗体价格、S期激酶活化蛋白DBF4A抗体结构式、批发、用途等信息,欢迎咨询。除供应S期激酶活化蛋白DBF4A抗体外,还可为您提供植物S-鸟氨酸转氨酶(OTC)检测试剂盒、蘑菇丝氨酸蛋白酶(PRSS)检测试剂盒、鸭免疫球蛋白G(IgG)检测试剂盒等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海基免客户服务电话,售前、售后均可联系。
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