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细胞周期调控蛋白SDP35抗体

供货周期： 7天

品牌： Abcam

型号： 0.1ml/100μg

货号：

报价： ¥1

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产品介绍

细胞周期调控蛋白SDP35抗体英文名称 Anti-DEPDC1

中文名称细胞周期调控蛋白SDP35抗体

别名 Cell cycle control protein SDP35; DEP domain containing 1; DEP domain containing protein 1A; DEP domain-containing protein 1A; DEP.8; DEP1A_HUMAN; DEPDC 1; DEPDC 1A; DEPDC1; DEPDC1-V2; Depdc1a; FLJ20354; SDP 35; SDP35.

公司细胞周期调控蛋白SDP35抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep

产品类型一抗

研究领域肿瘤肿瘤细胞生物标志物

蛋白分子量 predicted molecular weight: 93kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human DEPDC1 (606-660aa)

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

细胞周期调控蛋白SDP35抗体产品介绍

Function : May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.

Subunit : Isoform 2 and isoform 5 can form homodimers and heterodimers. Interacts with ZNF224.

Subcellular Location : Nucleus. Note=Co-localizes with ZNF224 at the nucleus.

Tissue Specificity : Expressed in testis. Up-regulated in bladder cancer cells (at protein level).

Similarity : Contains 1 DEP domain.

Contains 1 Rho-GAP domain.

【存储要求】连续使用时4°C存储，保质期六个月；细胞周期调控蛋白SDP35抗体期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。

实验的用途：

1）WB：Western Blotting 免疫印迹

2）IH：Immunohistochemistry 免疫组化

3）IH(P)：Immunohistochemistry Parraffin sections 免疫组化(石蜡)

4）IH(F)：Immunohistochemistry Frozen sections 免疫组化(冰冻)

5）IC：Immunocytochemistry 免疫细胞化学