浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Mouse, Rat, Chicken, Pig, Cow, Horse
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学 发育生物学 信号转导 细胞周期蛋白 转录调节因子
蛋白分子量 predicted molecular weight: 41kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human DRG1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GTP发育调控结合蛋白1抗体产品介绍 May play a role in cell proliferation, differentiation and death.High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
Function : Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest.
Subunit : Interacts (via its C-terminal) with TAL1. Interacts with ZC3H15; the interaction forms a polysomal DRG1-DFRP1/ZC3H15 complex which provides protein stability to DRG1 possibly by blocking poly-ubiquitination. Interacts with STK16; the interaction phosphorylates STK16
Subcellular Location : Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes.
Tissue Specificity : High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
Post-translational modifications : Sumoylated by UBE2I in response to MEKK1-mediated stimuli.
Similarity : Belongs to the GTP1/OBG family.
Contains 1 G (guanine nucleotide-binding) domain.
Database links : UniProtKB/Swiss-Prot: Q9Y295.1