SERPINB13 人丝氨酸蛋白酶抑制剂B13(Serpin B13)ELISA Kit

SERPINB13 人丝氨酸蛋白酶抑制剂B13(Serpin B13)ELISA Kit

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SERPINB13 up regulateS TAFI activation by inhibiting the protein C activation. SERPINB13 is an significant regulator in the equilibrium between coagulation and fibrinolysis by differentially inhibiting the activation of TAFI and of Protein-C. SERPINB13 belongs to the serpin serine proteinase inhibitor family. SERPINAB13 protein inhibits plasminogen activators as well as activated protein C.

SERPINB13 is secreted in plasma and liver. SERPINB13  is involved in cell inflammation， proliferation， apoptosis， tumour cell migration， invasion， and metastasis. SERPINB13 controls the invasive potential of renal cell carcinoma by inhibiting urinary plasminogen activator secreted by the cells. SERPINA5 plays a role in regulating key serine proteases involved in metastatic prostate disease. The heparin binding site of SERPINB13 inhibitor is protease-dependent.

SERPINB13 人丝氨酸蛋白酶抑制剂B13(Serpin B13)ELISA Kit

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免疫组化实验是利用抗原与抗体特异性结合的原理，通过化学反应使标记抗体的显色剂 (荧光素、酶、金属离子、同位素) 显色来确定组织细胞内抗原(多肽和蛋白质)，对其进行定位、定性及定量的研究。免疫组化实验中常用的抗体为单克隆抗体和多克隆抗体。单克隆抗体是一个B淋巴细胞克隆分泌的抗体，应用细胞融合杂交瘤技术免疫动物制备。多克隆抗体是将纯化后的抗原直接免疫动物后，从动物血中所获得的免疫血清，是多个B淋巴细胞克隆所产生的抗体混合物。

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