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当前位置: 顺元生物 > 常用生化试剂 > 人肿瘤坏死因子相关凋亡诱导因子配体

人肿瘤坏死因子相关凋亡诱导因子配体

供货周期: 7天
品牌:
型号: 10μg
货号: CYT-546
报价: ¥700
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产品介绍
Recombinant Human TNF-Related Apoptosis Inducing Ligand/Apo2L (114-281)人肿瘤坏死因子相关凋亡诱导因子配体
Synonyms Tumor necrosis factor ligand superfamily member 10, TNF-related apoptosis-inducing ligand, Protein TRAIL, Apo-2 ligand, Apo-2L, CD253 antigen, TL2, APO2L, TNFSF10.
Introduction TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family.
In humans, the gene that encodes for TRAIL is located at chromosome 3q26.
TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
Description Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids (114-281) and having a molecular mass of 19.6 kDa. The sTRAIL is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless liquid.
Formulation TRAIL in 20mM Tris-HCl pH-7.5, 300mM NaCl, 0.1mM DTT & 10% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence MVRERGPQRV AAHITGTRGR SNTLSSPNSK NEKALGRKIN SWESSRSGHS FLSNLHLRNGELVIHEKGFY YIYSQTYFRF QEEIKENTKN DKQMVQYIYK YTSYPDPILL MKSARNSCWSKDAEYGLYSI YQGGIFELKE NDRIFVSVTN EHLIDMDHEA SFFGAFLVG.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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» TRAIL Human
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上海顺元生物科技有限公司

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310116002748169

成立日期

2012-11-29

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人肿瘤坏死因子相关凋亡诱导因子配体由上海顺元生物科技有限公司为您提供,货号CYT-546,规格:10μg,CAS号:,如您想了解更多关于人肿瘤坏死因子相关凋亡诱导因子配体价格、人肿瘤坏死因子相关凋亡诱导因子配体结构式、批发、用途等信息,欢迎咨询。除供应人肿瘤坏死因子相关凋亡诱导因子配体外,还可为您提供人失效同系物2(DAB2)ELISA kit、大鼠细胞色素P450 2B1(Cyp2b1)ELISA kit、植物1,5-二磷酸核酮糖羧化酶/加氧酶(RuBisCO)ELISA Kit等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,顺元生物客户服务电话,售前、售后均可联系。
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