人活化素-A

人活化素-A Recombinant Human Activin-A
Catalogue Number  CYT-569    
Synonyms  Activin Beta-A chain, Erythroid differentiation protein, EDF, FRP, Activin-A, Inhibin-B, Inihibin-Beta A chain.    
Introduction  Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits.
Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, Inhibins are also thought to play a role in the control of gametogenesis, and embryonic and fetal development.    
Description  Activin-A Human Recombinant also called Inhibin-Beta A chain produced in E.Coli is a single monomeric, non-glycosylated, polypeptide chain containing 116 amino acids fragment (311-426) and having an amino-terminal hexa-histidine tag, having a total molecular weight of 17.47 kDa.
The Activin-A is purified by standard chromatographic techniques.    
Source  Escherichia Coli.    
Physical Appearance  Sterile Filtered clear solution.    
Formulation  Activin-A is supplied in 20mM Tris-HCl, 1mM EDTA and 50% glycerol.    
Stability  Store Inhibin-Beta, Alpha chain at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.    
Purity  Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.    
Usage  ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.    
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