胰高血糖素样肽—1的生理作用及临床应用

Stylus-based surface profiling is a standard technique for accurate, repeatable surface shape, topography and step height measurement in applications ranging from semiconductor R&D to solar cell QC.

文献名： Structural, morphological and optical properties of Bi NPs obtained by laser ablation and their selective detection of L-cysteine 作者： Ramon Gabriel Teixeira Rosaa, Celso de Araujo Duartea , Wido Herwig Schreinera, Ney Pereira Mattoso Filhoa, Arandi Ginane Bezerra Jr.b, Andersson Barisonc, Fernanda Maria Marins Ocamposc a Departamento de Física, Universidade Federal do Paraná Centro Politécnico, CP 19044, 81531-990 Curitiba (PR), Brazil b Departamento Acadêmico de Física, Universidade Tecnológica Federal do Paraná, 80230-901 Curitiba (PR), Brazil c Departamento de Química, Universidade Federal do Paraná Centro Politécnico, CP 19081, 81531-990 Curitiba (PR), Brazil 摘要：In the present work we show the results of the investigation of the properties of bismuth nanoparticles (NPs) obtained by the laser ablation in water. The samples were characterized by various techniques: UV/vis spectroscopy, dynamic light scattering, transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, nuclear magnetic resonance and zeta potential. The NPs were metallic and surface oxidated, exhibiting absorption peak at 257 nm due to the surface plasmon resonance. The interaction between the NPs and various amino acids was studied and revealed a selective sensibility to cysteine on a range of concentration from 80 to 720 μM, which we attribute to a dimerization of cysteine to cystine probably complexed to the nanoparticle surface by electrostatic interactions, leading to the modification of the NP absorption spectrum. 关键词：Bismuth; Nanoparticles; Laser ablation; Cysteine

纯水是制备溶出溶剂或生物相关溶液的重要成分，因此水质的好坏会影响结果。一旦水质选择不当，就会引入污染物，主要有以下几种类型。使用高质量纯水来制备溶出溶剂，是获取精确、可重现结果并满足监管要求的重要保障。

双螺杆挤出技术是一种用于聚合物行业新材料开发的成熟技术。作为一种高效且连续的 混合工艺，其可以提供高灵活性并对工艺参数进行严格控制。近年来，该技术已推广到其 他应用领域，制药和食品行业加大了对挤出工艺的采用力度。在这些行业中，要完全发挥应用潜力，需要满足特定的设备要求并使用专用附件。 赛默飞可提供采用卫生级设计的专用双螺杆挤出机和附件，帮助研究人员开发下一代新型食品、生物材料和药物。