重组人白介素17D(Human IL-17D)
ProSpec(蛋白质专家)是以色列一家具有超过16年历史的,专业从事细菌来源重组蛋白生产的先进生物技术公司。ProSpec生产多种细胞因子、生长因子、趋化因子、激素、酶、病毒抗原和许多其他重组蛋白。在研究团队和科学家们的努力下,ProSpec已经拥有超过1700种可用于癌症、细胞凋亡、发育、内分泌学、免疫学、神经科学、蛋白酶及干细胞研究用重组蛋白、多肽和抗体。10多年蛋白纯化方面的经验使ProSpec公司生产成本低、产量高、效率高,其蛋白产品不仅纯度高、生物活性高,价格也非常具有优势。同时ProSpec针对客户的需要提供自定义重组蛋白生产服务。
ProSpec向客户提供蛋白质产品、服务和技术授权。因为创新的产品、卓越的客户服务和对细节的注重,ProSpec在科学界建立了良好的信誉,具有广泛的客户群,包括世界各地的学术、政府研究机构,生物技术和制药企业以及医院和基准实验室。
热门产品
Adiponectin 脂连蛋白;
BDNF 神经营养因子
bFGF碱性成纤维生长因子
BMP-7 骨形态发生蛋白-7
EGF上表皮生长因子
follistatin卵泡休止素
GMCSF粒—巨噬细胞集落刺激因子
IGF1胰岛素样生长因子1
Leptin 瘦素
PDGF-BB血小板源性生长因子-BB
Myostatin 肌肉生长抑制素
Prolactin 催乳素
RANKL细胞核因子κB受体活化因子配基
SCF 干细胞因子
TGF Beta3转化生长因子-β3
TNF Alpha 肿瘤坏死因子α
VEGF 血管内皮生长因子
白介素系列
重组人白介素17D(Human IL-17D)
Catalogue Number | CYT-876 |
Synonyms | Interleukin 17D, Interleukin 27, IL-17D, IL-27, IL27, Interleukin-17D, Interleukin-27, IL17D. |
Introduction | IL17D modulates immune responses indirectly by stimulating the production of myeloid growth factors and chemokines, as well as suppressing the proliferation of myeloid progenitors. IL17D is expressed in the skeletal muscle, heart, adipose tissue, lung, pancreas, and nervous system. Among IL-17 family members, IL17D is most closely related to IL17B, sharing 27% aa sequence identity. The treatment of endothelial cells with IL17D cytokine stimulates the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by IL17D cytokine is NF-kappa B-dependent. |
Description | Interleukin-17D Human Recombinant (18-202) produced in E.Coli is a non-glycosylated disulfide-linked homodimer containing 2 polypeptide chains of 185 amino acids each and having a molecular mass of 40kDa. The IL-17D is purified by proprietary chromatographic techniques. |
Source | Escherichia Coli. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | Lyophilized from a 0.2μm filtered solution in Acetonitrile and TFA. |
Solubility | It is recommended to reconstitute the lyophilized IL-17D in sterile 18M-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Stability | Lyophilized IL17D although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-17D should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Purity | Greater than 97.0% as determined by SDS-PAGE. |
Amino Acid Sequence | APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPREQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR YLPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRSVYT EAYVTIPVGC TCVPEPEKDA DSINSSIDKQ GAKLLLGPND APAGP. |
Biological Activity | Immobilized rHuIL-17D binds to rHuIL-17BR with EC50 less than 2μg/ml. |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Related Products | ? IL 17 A/F Mouse? IL 17 Human? IL 17 Human, HEK? IL 17 Human, His? IL 17 Mouse? IL 17 Rat? IL 17A/F Human? IL 17A/F Rat? IL 17B Human? IL 17E Human? IL 17E Rat? IL 17F His Human? IL 17F Human, HEK? IL17B Human, His? IL17E Mouse? IL17F Human? IL17F Mouse? IL17F Rat |
更多
企业名称
上海高创化学科技有限公司
企业信息已认证
企业类型
信用代码
310228001353263
成立日期
2010-06-05
注册资本
10
经营范围
从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海高创化学科技有限公司
公司地址
上海市涞亭南路888弄238号
客服电话