CAY10505|10mg|K1351-上海高创化学科技有限公司

SKU:K1351		M. Wt:289.28
Formula:C14H8FNO3S		Solubility:No
Purity:>99%		Storage:2 years at -20 degrees centigrade
CAS No.:1218777-13-9		Synonyms:N/A
Chemical NameN/A

Description	CAY10505
Targets	PI3K-gamma
IC50	33 nM
In vitro	CAY10505 can inhibit PI3K-gamma with IC50 of 33 nM.
In vivo	Five weeks of DOCA administration were followed by 7 days of daily administration of PI3K-gamma inhibitor (5-[[5-(4-fluorophenyl)-2-furanyl]methylene]-2,4-thiazolidinedione (CAY10505), 0.6 mg.kg(-1), per os (p.o.)), atorvastatin (30 mg.kg(-1), p.o.), and losartan (25 mg.kg(-1), p.o.) (positive control of hypertension), which significantly improved acetylcholine-induced endothelium dependent relaxation, serum nitrate and (or) nitrite level, glutathione level, and the vascular endothelial lining in hypertensive rats.
Clinical Trials	N/A
Features	N/A

Description

CAY10505

Targets

PI3K-gamma

IC50

33 nM

In vitro

CAY10505 can inhibit PI3K-gamma with IC50 of 33 nM.

In vivo

Five weeks of DOCA administration were followed by 7 days of daily administration of PI3K-gamma inhibitor (5-[[5-(4-fluorophenyl)-2-furanyl]methylene]-2,4-thiazolidinedione (CAY10505), 0.6 mg.kg(-1), per os (p.o.)), atorvastatin (30 mg.kg(-1), p.o.), and losartan (25 mg.kg(-1), p.o.) (positive control of hypertension), which significantly improved acetylcholine-induced endothelium dependent relaxation, serum nitrate and (or) nitrite level, glutathione level, and the vascular endothelial lining in hypertensive rats.

Clinical Trials

N/A

Features

N/A

工商信息

企业名称

上海高创化学科技有限公司

企业信息已认证

企业类型

信用代码

310228001353263

成立日期

2010-06-05

注册资本

经营范围

从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

CAY10505由上海高创化学科技有限公司为您提供，货号K1351，规格：10mg，CAS号：1218777-13-9，如您想了解更多关于CAY10505价格、CAY10505结构式、批发、用途等信息，欢迎咨询。除供应CAY10505外，还可为您提供热灭活胎牛血清（澳大利亚）、热灭活马血清（新西兰）、超级新生牛血清（无支原体）等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海高创客户服务电话，售前、售后均可联系。