Omecamtiv mecarbil (CK-1827452)|2mg|K1349-上海高创化学科技有限公司

SKU:K1349		M. Wt:401.43
Formula:C20H24FN5O3		Solubility:No
Purity:>99%		Storage:2 years at -20 degrees centigrade
CAS No.:873697-71-3, 921625-14-1		Synonyms:CK-1827452, CK1827452
Chemical NameN/A

Description	Omecamtiv mecarbil (CK-1827452)
Targets	N/A
IC50	N/A
In vitro	Omecamtiv mecarbil selectively activates cardiac myosin by increasing the myosin ATPase rate. [1] In isolated cardiac myocytes, Omecamtiv mecarbil results in increase of myocyte contractility and overcomes of the myosin inhibitor BDM without increasing the calcium transient or inhibiting the PDE pathway. [1]
In vivo	In conscious dogs with myocardial infarction (MI-sHF), Omecamtiv mecarbil leads to a significant increase in wall thickening (25%), stroke volume (44%), cardiac output (22%) and left ventricular (LV) systolic ejection time (26%).
Clinical Trials	N/A
Features	N/A

Description

Omecamtiv mecarbil (CK-1827452)

Targets

N/A

IC50

N/A

In vitro

Omecamtiv mecarbil selectively activates cardiac myosin by increasing the myosin ATPase rate. [1] In isolated cardiac myocytes, Omecamtiv mecarbil results in increase of myocyte contractility and overcomes of the myosin inhibitor BDM without increasing the calcium transient or inhibiting the PDE pathway. [1]

In vivo

In conscious dogs with myocardial infarction (MI-sHF), Omecamtiv mecarbil leads to a significant increase in wall thickening (25%), stroke volume (44%), cardiac output (22%) and left ventricular (LV) systolic ejection time (26%).

Clinical Trials

N/A

Features

N/A

工商信息

企业名称

上海高创化学科技有限公司

企业信息已认证

企业类型

信用代码

310228001353263

成立日期

2010-06-05

注册资本

经营范围

从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

Omecamtiv mecarbil (CK-1827452)由上海高创化学科技有限公司为您提供，货号K1349，规格：2mg，CAS号：873697-71-3，如您想了解更多关于Omecamtiv mecarbil (CK-1827452)价格、Omecamtiv mecarbil (CK-1827452)结构式、批发、用途等信息，欢迎咨询。除供应Omecamtiv mecarbil (CK-1827452)外，还可为您提供含铁牛血清（新西兰）、重组人半乳糖凝集素3/Human LGALS3 His、热灭新生牛血清（新西兰）等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海高创客户服务电话，售前、售后均可联系。