MK 3207 HCl|2mg|K1346-上海高创化学科技有限公司

SKU:K1346		M. Wt:594.05
Formula:C31H29F2N5O3.HCl		Solubility:No
Purity:>99%		Storage:2 years at -20 degrees centigrade
CAS No.:957116-20-0		Synonyms:N/A
Chemical NameN/A

Description	MK 3207 HCl
Targets	CGRP
IC50	0.12 nM
In vitro	Although has affinity for AMY1 (CTR/RAMP1) receptor with a Ki value of 0.75 nM, MK 3207 displays marked selectivity for human CGRP receptor versus related human AM1 (CLR/RAMP2) receptor, AM2 (CLR/RAMP3) receptor, AMY3 (CTR/RAMP3) receptor, and CTR with Ki values of 16.5 uM, 0.156 uM, 0.128 uM and 1.9 uM, respectively.
In vivo	Administration of MK 3207 produces a concentration-dependent inhibition of capsaicin-induced dermal vasodilation in rhesus monkeys, blocking the blood flow increase with an EC50 of 0.8 nM and an EC90 of 7 nM, respectively.
Clinical Trials	N/A
Features	N/A

Description

MK 3207 HCl

Targets

CGRP

IC50

0.12 nM

In vitro

Although has affinity for AMY1 (CTR/RAMP1) receptor with a Ki value of 0.75 nM, MK 3207 displays marked selectivity for human CGRP receptor versus related human AM1 (CLR/RAMP2) receptor, AM2 (CLR/RAMP3) receptor, AMY3 (CTR/RAMP3) receptor, and CTR with Ki values of 16.5 uM, 0.156 uM, 0.128 uM and 1.9 uM, respectively.

In vivo

Administration of MK 3207 produces a concentration-dependent inhibition of capsaicin-induced dermal vasodilation in rhesus monkeys, blocking the blood flow increase with an EC50 of 0.8 nM and an EC90 of 7 nM, respectively.

Clinical Trials

N/A

Features

N/A

工商信息

企业名称

上海高创化学科技有限公司

企业信息已认证

企业类型

信用代码

310228001353263

成立日期

2010-06-05

注册资本

经营范围

从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

MK 3207 HCl由上海高创化学科技有限公司为您提供，货号K1346，规格：2mg，CAS号：957116-20-0，如您想了解更多关于MK 3207 HCl价格、MK 3207 HCl结构式、批发、用途等信息，欢迎咨询。除供应MK 3207 HCl外，还可为您提供大鼠胆囊收缩素/缩胆囊素八肽(CCK-8)ELISA Kit、重组大鼠抵抗素(Rat Resistin)、特级新生牛血清（无支原体）等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海高创客户服务电话，售前、售后均可联系。