Recombinant Human S100 Calcium Binding Protein A1(S100A1)

S100A1 Human
S100 Calcium Binding Protein A1 Human Recombinant
Catalog No. PRO-364

Synonyms:
Protein S100-A1, S100 calcium-binding protein A1, S-100 protein alpha subunit, S-100 protein alpha chain, S100A1, S100A, S100, S100-alpha, S100-A1.

Introduction:
S100A1 is a member of the S100 family of calcium binding proteins with EF-hand type Ca+2 binding motive. S100A1 (Calcium Binding Protein A1) is involved in the activation of sarcoplasmatic calcium release and the regulation of intermediate filament polymerization. S100A1 may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of S100A1 has been implicated in cardiomyopathies.
S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21.

Description:
S100A1 Human Recombinant full length protein expressed in E.coli is antibody reactive.
The S100A1 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered clear solution.

Formulation:
S100A1 at 0.2mg/ml in 20mM HEPES-KOH, pH7.0, 50mM NaCl, 1mM EDTA and 1mM DTT.

Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by SDS-PAGE.

Activity:
~3 nmol/mg/min using phosphatidylinositol as substrate.

Applications:
• ELISA
• Inhibition Assays
• Western Blotting

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» S100A10 Human
» S100A11 Human
» S100A4 Human
» S100A4 Human, His
» S100A6 Mouse
» S100B Human
» S100B Human, GST
» S100P Human
» S100Z Human