gAcrp30 Human
Globular Adiponectin Human Recombinant
Catalog No. CYT-615
Synonyms:
Acrp30, AdipoQ, GBP-28, APM-1, ACDC.
Introduction:
gAcrp30 globular protein, exists as a result of proteolytic processing of adiponectin. Adiponectin is manufactured and secreted solely by adipocytes, and is a highly obtained plasma protein, accounting for up to 0.05% of total serum protein. Similar to Adiponectin, gAcrp30 is able of lowering hyperglycemia and reversing insulin resistance. In addition, gAcrp30 is an significant protein that is involved in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids. AdipoR1 & AdipoR2 are the 2 signaling receptors for adiponectin and gAcrp30 that were recently been identified.
Description:
gAcrp30 Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated, Polypeptide chain containing 145 amino acids and having a molecular mass of 16690 Dalton.
The gAcrp30 is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Formulation:
Sterile filtered and lyophilized from 1mg/ml in 10mM Tris pH-8 & 0.75mM DTT.
Solubility:
We recommended reconstituting gAcrp30 at a concentration of 0.1-1mg per ml with 5mM Tris pH-8 and 0.75mM DTT which can then be further diluted to other aqueous solutions.
Stability:
For long term, store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
Reconstituted protein can be stored at 4°C for a limited period of time two weeks.
Purity:
Greater than 97% as determined by HPLC and SDS PAGE.
Amino Acid Sequence:
MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN
Biological Activity:
gAcrp30 activity is determined by its ability to inhibit the proliferation of mouse M1 cells. The expected ED50 for this effect is 1.0 – 2.5 μg/ml.
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals
企业名称
上海高创化学科技有限公司
企业信息已认证
企业类型
信用代码
310228001353263
成立日期
2010-06-05
注册资本
10
经营范围
从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
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