重组人胶质细胞成熟因子-γ(Human GMFG)

GMFG Human

Glia Maturation Factor Gamma Human Recombinant

Catalog No. CYT-632 

Synonyms:

Glia maturation factor gamma, GMF-gamma, GMFG, MGC126867.



Introduction:

GMFG is a hematopoietic-specific protein that mediates the pluripotentiality and lineage commitment of human hematopoietic stem cells. Glia maturation factor gamma is a cytokine-responsive protein in EPO-induced and G-CSF-induced hematopoietic lineage development. Glia maturation factor also acts as a Nerve Growth Factor in nervous system development, angiogenesis and immune function. GMFG possesses hematopoietic tissue-specific gene expression, a promoter concentrated with high-score hematopoiesis-specific transcription factors, and molecular coevolution with a rudimentary blood/immune system.



Description:

Glia Maturation Factor-Gamma (GMF-Gamma) Human Recombinant produced in E.Coli is a signle, non-glycosylated, polypeptide chain containing 142 amino acids and having a total molecular mass of 16.8 kDa.

Glia Maturation Factor-Gamma, GMF-Gamma, Human Recombinant is purified by proprietary chromatographic techniques.



Source:

Escherichia Coli.



Physical Appearance:

Sterile Filtered colorless clear solution.



Formulation:

The GMF-gamma protein contains 20mM Tris-HCL pH-8, 1mM DTT, 1mM EDTA and 10% Glycerol.



Stability:

Store at 4°C if entire vial will be used within 2-4 weeks.

Store, frozen at -20°C for longer periods of time.

Please avoid freeze thaw cycles.



Purity:

Greater than 90.0% as determined by SDS-PAGE.



Amino acid sequence:

MSDSLVVCEV DPELTEKLRK FRFRKETDNA AIIMKVDKDR QMVVLEEEFQ NISPEELKME LPERQPRFVV YSYKYVHDDG RVSYPLCFIF SSPVGCKPEQ

QMMYAGSKNR LVQTAELTKV FEIRTTDDLT EAWLQEKLSF FR.



Usage:

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. 

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