重组小鼠干扰素-β His(Mouse IFN b His)

IFN b Mouse, His

Interferon Beta Mouse Recombinant, His Tag

Catalog No. CYT-651 

Synonyms:

Leukocyte interferon, B cell interferon, Type I interferon, IFNB1, IFB, IFF, IFNB, IFN-b 1b, MGC96956.



Introduction:

Interferon-beta 1b has antiviral, antibacterial and anticancer activities.

Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein.

Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.



Description:

Interferon beta Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (22-182 a.a.) and having a molecular mass of 22 kDa. Mouse IFN beta is fused to 20 amino acid at N-terminus and purified by proprietary chromatographic techniques.



Source:

Escherichia Coli.



Physical Appearance:

Sterile filtered colorless solution.



Formulation:

The IFN-Beta contains 20mM Tris-HCl buffer pH-8, 0.1M NaCl and 30% glycerol.



Stability:

Store at 4°C if entire vial will be used within 2-4 weeks.

Store, frozen at -20°C for longer periods of time.

For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles.



Purity:

Greater than 95% as determined by Analysis by SDS-PAGE.



Sequence:

MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN.



Usage:

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. 

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