重组人肿瘤型M2丙酮酸激酶(Human PKM2)

PKM2 Human
Tumor Type M2 Pyruvate Kinase Human Recombinant
Catalog No. PKA-339

Synonyms:
Pyruvate kinase isozymes M1/M2, EC 2.7.1.40, Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1, M2PK, PKM2, PK3, PK2, PKM, TCB, OIP3, MGC3932, Tumor Type M2 Pyruvate Kinase.

Introduction:
Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence.

Description:
PKM2 Human Recombinant is produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 62400 Dalton with an amino-terminal hexahistidine tag.
The PKM2 is purified by standard chromatographic techniques.

Source:
Escherichia Coli

Physical Appearance:
Sterile Filtered clear solution.

Formulation:
PKM2-His is supplied in 1x PBS and 50% glycerol.

Stability:
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

Purity:
Greater than 95.0% as determined by:
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-PAGE

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.