Recombinant Human CD4 (26-226)

CD4 Human (26-226)
CD-4 (26-226 a.a.) Human Recombinant
Catalog No. CYT-313

Synonyms:
gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.

Introduction:
CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.

Description:
CD-4 Human Recombinant encoding amino acids 26-226.

Source:
Escherichia Coli.

Physical Appearance:
Sterile filtered liquid.

Formulation:
Recombinant Human protein at 100µg/ml in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.

Stability:
Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months.
Please avoid freeze-thaw cycles.

Characterization:
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa.

Applications:
· ELISA
· Inhibition Assays
· Western Blotting

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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