HSA Recombinant, Mammalian
Human Serum Albumin Recombinant - Mammalian derived
Catalog No. PRO-369
Synonyms:
Serum albumin, ALB, PRO0883, PRO0903, PRO1341, DKFZp779N1935, GIG20, GIG42, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696, SA, HSA.
Introduction:
Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly (A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain.
HSA is widely used to stabilize blood volume generally from donors but the fear of contamination such as HIV & Hepatitis has enticed great interest in the recombinant form which is identical to the natural blood.
Description:
Recombinant Human HSA produced in mammalians is a single, glycosylated, polypeptide chain containing 585 amino acids and having a molecular mass of 66441 Dalton.
The HSA-m is purified by proprietary chromatographic techniques.
Source:
Mammalian Cell Line
Physical Appearance:
Sterile Filtered yellowish liquid formualtion.
Formulation:
50mM sodium phosphate, 1mM sodium chloride, pH-7: aseptically filtered (0.2µm).
Stability:
HSA should be stored between at tempertures below 30°C.
NOTE: Do not freeze!
Purity:
Greater than 98.% as determined by both:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Applications:
Formulation of Protein Therapeutics
Cell Storage: Cryopreservation
Vaccine formulation and manufacturing
Development of mammalian cell cultures
Infertility treatments
Coating for medical devices
Drug delivery
In vivo diagnostics
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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企业名称
上海高创化学科技有限公司
企业信息已认证
企业类型
信用代码
310228001353263
成立日期
2010-06-05
注册资本
10
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从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
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