MAGE1 Human
MAGE-1 Human Recombinant
Catalog No. PRO-311
Synonyms:
Melanoma-associated antigen 1, MAGE-1 antigen, Antigen MZ2-E, Cancer/testis antigen 1.1, CT1.1, MAGEA1, MAGE1, MAGE1A, MGC9326.
Introduction:
Melanoma antigen family A 1 belongs to the MAGEA gene family, whose members encode proteins with 50 to 80% sequence identity to each other. The MAGEA genes which are clustered at chromosomal location Xq28, have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Human malignant neoplasms carry rejection antigens that are recognized by the patients autologous, tumor directed and specific, cytolytic, CD8+T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs).
Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Description:
MAGE1 Human Recombinant full length protein expressed in E.coli, MAGE-1 is antibody reactive. The MAGE-1 is fused to a GST tag purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear solution.
Formulation:
MAGE-1 in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Applications:
• ELISA
• Inhibition Assays
• Western Blotting
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
更多
更多
企业名称
上海希美化学有限公司
企业信息已认证
企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
公司地址
上海市松江区陆家圈路168弄113号
客服电话