Ephrin A1 Human
Ephrin A1 Human Recombinant
Catalog No. PRO-495
Synonyms:
Ephrin-A1, EPH-related receptor tyrosine kinase ligand 1, LERK-1, Immediate early response protein B61, Tumor necrosis factor alpha-induced protein 4, EFNA1, EPLG1, LERK1, TNFAIP4, B61, EFL1, ECKLG.
Introduction:
Ephrin A1 is a member of the ephrin (EPH) family. Ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases. Based upon their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are attached to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Class A ephrins are linked to the membrane by a GPI linkage and bind primarily to EphA receptors; Class B ephrins contain a membrane-spanning region and bind primarily to EphB receptors.
Both ephrins and Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos.
EFNA binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors.
Two transcript variations which encode different isoforms were identified through sequence analysis. During development the Eph receptor and their membrane-attached ligands, ephrins, show diverse expression patterns.
The ephrins and EPH-related receptors mediate developmental events, principally in the nervous system and in erythropoiesis. The critical roles of Eph and ephrins during development imply involvement of these genes in congenital disorders affecting the nervous system and other tissues.
Ephrins and Eph receptors are possibly involved in carcinogenesis.
Description:
Ephrin A1 Human Recombinant full length protein expressed in E.coli, shows a 47 kDa SDS-PAGE (Including GST).
The Ephrin A1 is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear solution.
Formulation:
Ephrin A1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Applications:
• ELISA
• Inhibition Assays
• Western Blotting
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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企业名称
上海希美化学有限公司
企业信息已认证
企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
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