Recombinant Mouse Bax GST Tag

Bax Mouse, GST
Bax Mouse Recombinant, GST
Catalog No. PRO-647

Synonyms:
Apoptosis regulator BAX membrane isoform alpha, Bax, Bcl2-associated X protein.

Introduction:
Bcl-2–associated X protein (Bax) belongs to the Bcl-2 protein family.
Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains.
Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary.
Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.

Description:
Bax Mouse Recombinant amino acid 1-171 produced in E.Coli is a single, non-glycosylated polypeptide chain.
The Mouse Bax is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered colorless solution.

Formulation:
The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.

Stability:
Mouse Bax although stable at 12°C for 1 week, should be stored desiccated below -18°C.
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Applications:
Input marker or positive control (Western Blotting).

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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