IGF-IR Human
Insulin-like Growth Factor-1 Receptor Human Recombinant
Catalog No. PKA-237
Synonyms:
Insulin-like growth factor 1 receptor, EC 2.7.10.1, Insulin-like growth factor I receptor, IGF-I receptor, CD221 antigen, CD221, IGFIR, JTK13, MGC18216, MGC142170, MGC142172.
Introduction:
The Insulin-like Growth Factor 1 (IGF-1) Receptor is a transmembranereceptorthat is activated by IGF-1and by the related growth factor IGF-II. It belongs to the large class of tyrosine kinasereceptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. IGF-1 plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscleand other target tissues.
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and Beta-subunits, which are disulfide-linked in a Beta-alpha-alpha-Beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the Beta-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
Description:
Insulin-like growth factor 1 receptor Human Recombinant encoding 1213-1367 amino acids expressed in E.coli, shows a 43kDa band on SDS-PAGE (Including GST tag).
IGF-IR is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile filtered liquid.
Formulation:
IGF-IR protein in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
Stability:
Store vial at -20ºC to -80ºC. When stored at the recommended temperature, this protein is stable for 12 months.
Please avoid freeze-thaw cycles.
Application And Suggested Dilutions:
• ELISA
• Inhibition Assays
• Western Blotting
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
更多
更多
企业名称
上海希美化学有限公司
企业信息已认证
企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
公司地址
上海市松江区陆家圈路168弄113号
客服电话