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当前位置: 上海希美化学 > 常用生化试剂 > 重组人主动粘着斑激酶(Human FAK1)

重组人主动粘着斑激酶(Human FAK1)

供货周期: 一周
品牌: Prospect Biosystems
规格: 1μg/5μg/10μg
货号: PKA-312
CAS号:
报价: 面议
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产品介绍

FAK1 Human
Active Focal Adhesion Kinase Human Recombinant
Catalog No. PKA-312

Synonyms:
Focal adhesion kinase 1, EC 2.7.10.2, FADK 1, pp125FAK, Protein-tyrosine kinase 2, FAK, FADK, FAK1.

Introduction:
FAK is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined.

Description:
Active Focal Adhesion Kinase full length Human Recombinant is a 146.7 kDa enzyme produced in Sf9 cells with an amino-terminal GST tag and purified via sequential chromatography. PTK2 is activated in-vitro by his tagged SRC.

Source:
Baculovirus, SF9 insect cells.

Formulation:
FADK is supplied in 50mM Tris pH-7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, & 50% Glycerol.

Biological Activity:
72 nmole of phosphate transferred to poly [Glu,Tyr] 4:1 substrate/minute/mg of total protein at 30°C. Activity determined at a final protein concentration of 4μg/ml.

Storage Conditions:
Store at 4°C if entire vial will be used within 1-2 weeks.
Store, frozen at -20°C to -80°C for longer periods of time.
Avoid multiple freeze-thaw cycles.

Dilution Buffer:
20mM Tris pH-7.5, 10% Glycerol, 0.02% Triton X-100, 0.1mg/ml BSA, 0.5mM Na3VO4, 2mM DTT.

Purity:
Greater than 70% as determined by SDS-PAGE.

Amino Acid Sequence:
MAPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRHNQTSL YKKAGTMAAA YLDPNLNHTP NSSTKTHLGT GMERSPGAME RVLKVFHYFE SNSEPTTWAS IIRHGDATDV
RGIIQKIVDS HKVKHVACYG FRLSHLRSEE VHWLHVDMGV SSVREKYELA HPPEEWKYEL RIRYLPKGFL NQFTEDKPTL NFFYQQVKSD YMLEIADQVD QEIALKLGCL EIRRSYWEMR GNALEKKSNY EVLEKDVGLK RFFPKSLLDS VKAKTLRKLI QQTFRQFANL NREESILKFF EILSPVYRFD KECFKCALGS SWIISVELAI GPEEGISYLT DKGCNPTHLA DFTQVQTIQY SNSEDKDRKG MLQLKIAGAP EPLTVTAPSL TIAENMADLI DGYCRLVNGT SQSFIIRPQK
EGERALPSIP KLANSEKQGM RTHAVSVSET DDYAEIIDEE DTYTMPSTRD YEIQRERIEL GRCIGEGQFG DVHQGIYMSP ENPALAVAIK TCKNCTSDSV REKFLQEALT MRQFDHPHIV KLIGVITENP VWIIMELCTL GELRSFLQVR KYSLDLASLI LYAYQLSTAL AYLESKRFVH RDIAARNVLV SSNDCVKLGD FGLSRYMEDS TYYKASKGKL PIKWMAPESI NFRRFTSASD VWMFGVCMWE ILMHGVKPFQ GVKNNDVIGR IENGERLPMP PNCPPTLYSL MTKCWAYDPS
RRPRFTELKA QLSTILEEEK AQQEERMRME SRRQATVSWD SGGSDEAPPK PSRPGYPSPR SSEGFYPSPQ HMVQTNHYQV SGYPGSHGIT AMAGSIYPGQ ASLLDQTDSW NHRPQEIAMW QPNVEDSTVL DLRGIGQVLP THLMEERLIR QQQEMEEDQR WLEKEERFLK PDVRLSRGSI DREDGSLQGP IGNQHIYQPVGKPDPAAPPK KPPRPGAPGH LGSLASLSSP ADSYNEGVKL QPQEISPPPT ANLDRSNDKV YENVTGLVKA VIEMSSKIQP APPEEYVPMV KEVGLALRTL
LATVDETIPL LPASTHREIE MAQKLLNSDL GELINKMKLA QQYVMTSLQQ EYKKQMLTAA HALAVDAKNL LDVIDQARLK MLGQTRPH.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

工商信息

企业名称

上海希美化学有限公司

企业信息已认证

企业类型

信用代码

310228001203103

成立日期

2009-05-31

注册资本

10

经营范围

化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

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重组人主动粘着斑激酶(Human FAK1)由上海希美化学有限公司为您提供,货号PKA-312,规格:1μg/5μg/10μg,CAS号:,如您想了解更多关于重组人主动粘着斑激酶(Human FAK1)价格、重组人主动粘着斑激酶(Human FAK1)结构式、批发、用途等信息,欢迎咨询。除供应重组人主动粘着斑激酶(Human FAK1)外,还可为您提供牛磷酸烯醇式丙酮酸羧激酶(PCK)ELISA Kit 、核苷二磷酸激酶A(NDPK-A)ELISA kit、鸡磷酸烯醇丙酮酸羧激酶,细胞质基质[GTP](PCK1)ELISA kit等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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