人二肽肽酶4（Human DPP4）

DPP4 Human
Human Dipeptidyl Peptidase-IV
Catalog No. ENZ-382

Synonyms:
DPP-IV, DPPIV, DPP4, DPP-4, Dipeptidyl Peptidase-IV, Dipeptidyl Peptidase-4, CD26, adenosine deaminase complexing protein 2, Dipeptidylpeptidase-IV, CD-26, ADABP, ADCP2, DPIV, TP103, DP-IV, DP-4, DP4.

Introduction:
Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense.

Source:
Human Placenta

Physical Appearance:
Filtered lyophilized (freeze-dried) powder.

Formulation:
Each 70ng were lyophilized from 29.1μl containing 2mM Tris-HCl, pH 8.0.

Solubility:
Add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Stability:
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. The lyophilized protein remains stable until the expiry date when stored at -20°C.

Biological Activity:
One unit is defined as the amount of enzyme which will hydrolyze 1μM of H-Gly-Pro-pNA per 1min at 25°C, pH 7.8.

Specific Activity:
13U/mg

Purity:
Greater than 95% as determined by SDS-PAGE.

Specifications:
The protein was prepared from tissue shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1and 2by FDA required tests. This product is intended for research useonly.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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