Argipressin
Argipressin
Catalog No. HOR-301
Synonyms:
Arginine vasopressin, AVP, Vasopressin, Argipressin, Antidiuretic Hormone, ADH.
Introduction:
Argipressin (Arginine vasopressin) is similar to a naturally occuring hormone also known as antidiuretic hormone (ADH) or vasopressin. ADH has two main effects in the body. Firstly, it acts on receptors in the kidney to retain water in the body, which helps to prevent excessive loss of water in the urine. Secondly, ADH causes narrowing of blood vessels (vasoconstriction), thereby limiting blood flow to a particular area of the body. Argipressin is derived from a preprohormone precursor that is synthesized in the hypothalamus, from which it is liberated during transport to the posterior pituitary. Most of it is stored in the posterior part of the pituitary gland to be released into the blood stream; some of it is also released directly into the brain. The vasopressins are peptides consisting of nine amino acids (nonapeptides). The amino acid sequence of arginine vasopressin is Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly, with the cysteine residues forming a sulfur bridge. The structure of oxytocin is very similar to that of the vasopressins: it is also a nonapeptide with a sulfur bridge and its amino acid sequence differs at only two positions.
Description:
Argipressin Synthetic is a single, non-glycosylated polypeptide chain containing 9 amino acids, having a molecular mass of 1084.2 Dalton and a Molecular formula of C46H65N16O12S2.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
The Argipressin was lyophilized with no additives.
Solubility:
It is recommended to reconstitute the lyophilized Argipressin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Stability:
Lyophilized Argipressin e although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Argipressin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity:
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Amino Acid Composition:
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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企业名称
上海希美化学有限公司
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信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
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