重组小鼠干扰素-β(Mouse IFN b)

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IFN b Mouse
Interferon Beta Mouse Recombinant
Catalog No. CYT-550 
Synonyms:
Leukocyte interferon, B cell interferon, Type I interferon, IFNB1, IFB, IFF, IFNB, IFN-b 1b, MGC96956.

Introduction:
Interferon-beta 1b has antiviral, antibacterial and anticancer activities.
Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein.
Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.

Description:
Interferon beta Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 162 amino acids and having a molecular mass of 19.8 kDa.
Mouse IFN beta is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Formulation:
IFN-b Mouse solution containing 10mM sodium phosphate pH-7.5 and 0.5M ammonium sulfate.

Stability:
Store the IFN-beta at 4°C for 4 weeks.
Do not freeze/thaw.

Purity:
Greater than 90.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Biological Activity:
Determined in a viral cytopathic effect inhibition assay.

Amino acid sequence:
MINYKQLQLQERTNIRKCQELLEQLNGKINLTYRADFKIPMEMTEKMQKS
YTAFAIQEMLQNVFLVFRNNFSSTGWNETIVVRLLDELHQQTVFLKTVLE
EKQEERLTWEMSSTALHLKSYYWRVQRYLKLMKYNSYAWMVVRAEIFR
NFLIIRRLTRNFQN.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. 
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