Rat Anti Mouse CD86 Biotin

CD86 Antibody, Biotin
CD86, Rat Anti-Mouse, Biotinylated
Catalog No. ANT-284

Synonyms:
B70, B7-2, LAB72, CD28LG2, FUN-1, BU63.

Type:
Rat Anti Mouse Monoclonal

Introduction:
CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.

Clone:
mB7-2

Immunogen:
Purified mouse LPS-activated B cells

Ig Subclass:
Rat IgG2a

Purification Method:
Protein-A

Protein concentration:
1mg/ml in PBS (after reconstitution).

Storage Procedures:
Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Reconstitution:
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4°C.

Antibody Properties:
Blocking and staining antibody. For staining, use 10µl/106 cells. Titer for blocking T cell activation should be determined by the investigator.

Available Conjugates:
This antibody is only available non-conjugated and conjugated to FITC.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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