Catalogue Number | ANT-235 | ||||
Synonyms | MYC, CMYC, C-MYS, V-MYC, P64. | ||||
Type | Polyclonal Rabbit Antibody. | ||||
Introduction | c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. | ||||
Clone | PPMYCSHG. | ||||
Description | Polyclonal antibodies are produced by immunizing rabbits with synthetic peptide (EQKLISEEDL) coupled to KLH. | ||||
Formulation | Serum with 0.02% sodium azide. | ||||
Stability / Shelf Life | 2 years at -20°C. 1 month at 4°C. | ||||
Dilution | Western Blotting: 1:500. | ||||
Applications | Western Blot, Immunoprecipitation. | ||||
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||||
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企业名称
上海希美化学有限公司
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信用代码
310228001203103
成立日期
2009-05-31
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10
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化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
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