关注
已关注
已认证
粉丝量 0
| Catalogue Number | ANT-210 | ||||||
| Synonyms | HIV-1 gp120, HIV1gp120, HIV-I gp120, HIVIgp120. | ||||||
| Type | Polyclonal Rabbit Antibody. | ||||||
| Introduction | Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells), macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosisin infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunityis lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genomeis converted to double-stranded DNAby a virally encoded reverse transcriptasethat is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integraseso that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latentand the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells. | ||||||
| Description | Rabbit Polyclonal Antibody to gp120 (HIV-1) serum. | ||||||
| Host | Rabbit. | ||||||
| Formulation | Each 0.5ml of Polyclonal Antibody serum was lyophilized in vials. | ||||||
| Immunogen | Recombinant HIV-1 gp120 produced in baculovirus expression system. | ||||||
| Stability | Stable for 2 yeas at -20o C. Avoid freeze/thaw cycles. | ||||||
| Applications | Binds to recombinant HIV-1 gp120 ELISA and Western Blot Optimal dilutions should be determined by the customer, based on titration. Suggested starting dilutions are listed belowWestern Blot: 1-500 to 1-1000. | ||||||
| ELISA | : 1:500 to 1000. | ||||||
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||||||
| Related Products |
|
更多
更多
企业名称
上海希美化学有限公司
企业信息已认证
企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
公司地址
上海市松江区陆家圈路168弄113号
客服电话
公司名称： 上海希美化学有限公司
公司地址： 上海市松江区陆家圈路168弄113号 联系人： 李保平 邮编： 201619
仪器信息网APP
展位手机站