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AKR1B1 Antibody(Center)
Cat.#: T0905
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P15121
Mol Weight: 36kDa
Size: 100ug
Description
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
Recommended Applications
WB, IHC, ELISA
Applications and Recommended Dilution Factors
WB: 1:50~100
IHC: 1:10~50
ELISA: 1:1,000
Species Reactivity
Human
Products Data
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Western blot analysis of anti-AKR1B1 Pab in Jurkat cell line lysates (35ug/lane).AKR1B1 (arrow) was detected using the purified Pab (1:60 dilution).
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AKR1B1 antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Specificity
This AKR1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111~141 amino acids from the Center region of human AKR1B1.
Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Names
AKR1B1 antibody, ADR antibody, ALDR1 antibody, ALR2 antibody, AR antibody, MGC1804 antibody, Aldose reductase antibody, Aldehyde reductase antibody, Aldo-keto reductase family 1 member B1 antibody
Description References
Steuber,H.,J. Mol. Biol. 379 (5), 991-1016 (2008)
Gleissner,C.A.,Arterioscler. Thromb. Vasc. Biol. 28 (6), 1137-1143 (2008)
Grundmann,U.,DNA Cell Biol. 9 (3), 149-157 (1990)
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企业名称
上海希美化学有限公司
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企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
公司地址
上海市松江区陆家圈路168弄113号
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公司名称： 上海希美化学有限公司
公司地址： 上海市松江区陆家圈路168弄113号 联系人： 李保平 邮编： 201619
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