AKAP12 antibody

AKAP12 antibody
Cat.#: S1911
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q02952
Mol Weight: 191.52kDa
Size: 100ul

Description
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

Recommended Applications
WB, IHC, ICC

Applications and Recommended Dilution Factors
WB: 1:500-1:3000
IHC: 1:100-1:250,IF:1:100-1:200
ICC: 1:100-1:200

Species Reactivity
Human

Other species have not been tested

Products Data 

Specificity
Synthetic peptide contain a sequence corresponding to a region within amino acids 1719 and 1782 of AKAP12

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
AKAP12 antibody, AKAP250 antibody, DKFZp686M0430 antibody, DKFZp686O0331 antibody, FLJ20945 antibody, FLJ97621 antibody, A-kinase anchor protein 12 antibody, Gravin antibody, Myasthenia gravis autoantigen antibody