adenylate kinase 1 antibody

adenylate kinase 1 antibody
Cat.#: S0972
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P00568
Mol Weight: 21.64kDa
Size: 100ul

Description
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data

 
Sample (30ug of whole cell lysate)
A: HCT116 12% SDS PAGE
diluted at 1:500

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 158 of adenylate kinase 1

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
AK1 antibody, - antibody, Adenylate kinase isoenzyme 1 antibody, ATP-AMP transphosphorylase 1 antibody, Myokinase antibody