ADAM15 antibody

ADAM15 antibody
Cat.#: S0305
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q13444
Mol Weight: 92.98kDa
Size: 100ul

Description
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human, Mouse

Other species have not been tested

Products Data 

A: Hep G2

7.5% SDS PAGE

diluted at 1:1000
 Sample (30ug of whole cell lysate)

A: NIH-3T3

7.5% SDS PAGE

ADAM15 antibody

diluted at 1:1000

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 225 of ADAM15

Storage Condition and Buffer
1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
ADAM15 antibody, MDC15 antibody, Disintegrin and metalloproteinase domain-containing protein 15 antibody, Metargidin antibody