ACVRL1 antibody

ACVRL1 antibody
Cat.#: S0740
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P37023
Mol Weight: 56.13kDa
Size: 100ul

Description
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human, Mouse

Other species have not been tested

Products Data 

diluted at 1:1000

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 109 and 281 of ACVRL1

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
ACVRL1 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, Serine/threonine-protein kinase receptor R3 antibody, TGF-B superfamily receptor type I antibody