ABCB7 antibody

ABCB7 antibody
Cat.#: S3225
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: O75027
Mol Weight: 82.78kDa
Size: 100ul

Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data

 
Sample (30ug of whole cell lysate)
A: A431
7.5% SDS PAGE
diluted at 1:1000

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 450 and 676 of ABCB7

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
ABCB7 antibody, ABC7 antibody, ASAT antibody, Atm1p antibody, EST140535 antibody, ATP-binding cassette sub-family B member 7, mitochondrial antibody, ATP-binding cassette transporter 7 antibody