AP2 gamma(TFAP2C)antibody
Cat.#: 2390-1
Rabbit Monoclonal Antibody
Clone ID: EP2692Y
Swiss Prot: Q92754
Mol Weight: 49kDa
Size: 100ul
Description
Transcription factor gene AP2-C (AP-2 gamma) belongs to a family of four closely related genes. The AP-2 transcription factor has been shown to play an important role in the development of tissues of ectodermal origin and has also been implicated in mammary oncogenesis (2). A physical and functional association between AP-2gamma transcription factor and the Wwox protein has been demonstrated. results suggest that Wwox tumor suppressor protein inhibits AP-2gamma oncogenic activity by sequestering it in the cytoplasm (2). P-2 gamma had been implicated in multiple functions during proliferation and differentiation based on its expression pattern in trophoblast, neural crest, and ectoderm cells in murine embryos. AP-2 gamma seems to be required in early embryonic development because it regulates the genetic programs controlling proliferation and differentiation of extraembryonic trophectodermal cells (3).
Recommended Applications
WB, IHC, ICC, FC
Applications and Recommended Dilution Factors
WB: 1:10,000 -50,000
IHC: 1:250 - 500
ICC: 1:100 - 250
FC: 1:50
Species Reactivity
Human
Cross reactivity determined by western blot only.
Products Data
Specificity
A synthetic peptide corresponding to residues in human AP2 gamma was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
TFAP2C antibody, AP2-GAMMA antibody, ERF1 antibody, TFAP2G antibody, hAP-2g antibody, Transcription factor AP-2 gamma antibody, Activating enhancer-binding protein 2 gamma antibody, Transcription factor ERF-1 antibody
Description References
1. Williamson JA, et al. Genomics 35(1):262-4, 1996
2. Ageilan RI, et al. Cancer Res 64(22): 8256-61, 2004
3. Werling U et al. Mol Cell Biol 22(9):3149-56, 2002
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企业名称
上海希美化学有限公司
企业信息已认证
企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
公司地址
上海市松江区陆家圈路168弄113号
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