Antithrombin III(SERPINC1)antibody

Antithrombin III(SERPINC1)antibody
Cat.#: 3671-1
Rabbit Monoclonal Antibody
Clone ID: EPR5371
Swiss Prot: P01008
Mol Weight: 55kDa
Size: 100ul

Description
Antithrombin III is a plasma protease inhibitor and a member of the serpin superfamily. It inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. Antithrombin III includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified, many of which are known to cause antithrombin-III deficiency (1).

Recommended Applications
WB, ICC

Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:50 - 100

Species Reactivity
Human

Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on (A) human plasma, (B) ovary cancer, and (C) human testis lysates using anti-Antithrombin III RabMAb (cat. #3671-1).

Specificity
A synthetic peptide corresponding to residues in human Antithrombin III was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. Supplied in PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA

Alternative Names
SERPINC1 antibody, AT3 antibody, ATIII antibody, MGC22579 antibody, Antithrombin-III antibody, Serpin C1 antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.