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Alpha 2 Macroglobulin(A2M)antibody
Cat.#: 3451-1
Rabbit Monoclonal Antibody
Clone ID: EPR4432
Swiss Prot: P01023
Mol Weight: 180kDa
Size: 100ul
Description
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. Alpha-2-macroglobulin is implicated in Alzheimer’s disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits (1).
Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors
WB: 1:10,000-50,000
IHC: 1:500-1,000
Species Reactivity
Human
Species cross-reactivity is based on WB analysis
Products Data
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Western blot analysis on human plasma lysate using anti-Alpha 2 Macroglobulin RabMAb (cat. #3451-1).
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Alpha 2 Macroglobulin RabMAb (cat. #3451-1).
Specificity
A synthetic peptide corresponding to residues in human Alpha 2 Macroglobulin was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
A2M antibody, CPAMD5 antibody, DKFZp779B086 antibody, S863-7 antibody, Alpha-2-macroglobulin antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody
Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
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上海希美化学有限公司
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公司名称： 上海希美化学有限公司
公司地址： 上海市松江区陆家圈路168弄113号 联系人： 李保平 邮编： 201619
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