ADH1A/1B/1C antibody

ADH1A/1B/1C antibody
Cat.#: 2980-1
Rabbit Monoclonal Antibody
Clone ID: EPR4440
Swiss Prot: P07327
Mol Weight: 40kDa
Size: 100ul

Description
ADH1A/1B/1C are class I alcohol dehydrogenases that consist of alpha, beta, gamma subunits, which are members of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenases, consisting of several homo- and heterodimers of the three subunits, exhibit high activity for ethanol oxidation and play a major role in ethanol catabolism. The alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. ADH1A is monomorphic and predominant in fetal and infant livers, whereas ADH1B and ADH1C are polymorphic and strongly expressed in adult livers.

Recommended Applications
WB, IHC, IP

Applications and Recommended Dilution Factors
WB: 1:1,000-10,000
IHC: 1:100 - 250
IP: 1:10 - 100

Species Reactivity
Human, Mouse, Rat

For Mouse, this antibody is recommended for WB only
Rat cross reactivity tested by western blot only

Products Data 

Specificity
A synthetic peptide corresponding to residues in human ADH1A/1B/1C was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
ADH1A antibody, ADH1 antibody, Alcohol dehydrogenase 1A antibody, Alcohol dehydrogenase subunit alpha antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.