20S Proteasome alpha3 antibody
Cat.#: S2829
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P25788
Mol Weight: 27.65kDa
Size: 100ul
Description
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
IHC: 1:100-1:500
Species Reactivity
Human
Other species have not been tested
Products Data
Sample (30ug of whole cell lysate)
A: Molt-4
12% SDS PAGE
diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded U87 xenograft , using 20S Proteasome alpha3 antibody at 1:100 dilution.
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 147 of 20S Proteasome alpha3
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
PSMA3 antibody, HC8 antibody, MGC12306 antibody, MGC32631 antibody, PSC3 antibody, Proteasome subunit alpha type-3 antibody, Macropain subunit C8 antibody, Multicatalytic endopeptidase complex subunit C8 antibody, Proteasome component C8 antibody
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企业名称
上海希美化学有限公司
企业信息已认证
企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
公司地址
上海市松江区陆家圈路168弄113号
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